Before we discuss Vitamin D for Depression we have to talk about some basics concept which is hard to describe.
What is depression?
At certain times in our lives, we all feel fed up, unhappy, and sad. Most of the time, these emotions last for a couple of days or perhaps a week, but they don’t interfere with our daily lives. Speaking to a friend or family member also helps to ease those feelings. And, when you have clinical depression, also known as major depression, these symptoms are not reducing, and for days, months, or even years, it can continue.
Vitamin D for depression? It may, according to some studies, but there is some conflicting evidence available. It seems that just as low thyroid can cause clinical depression, so can low vitamin D. Among depressed patients, dozens of studies have shown a high prevalence of vitamin D deficiency. Some studies have shown that low-dose vitamin D helps reduce different depression signs. As vitamin D and anxiety are remarkably safe is hazardous (about 36,000 suicides/year in the United States), it seems fair to ensure that those affected by this condition can continue a high normal vitamin D status.
If you have anxiety, systemic, or even high-dose treatment of vitamin D is recommended. And doses ranging from 5,000 IU / day (125 mcg) to 10,000 IU / day (250 mcg) are safe and effective in improving the stable vitamin D level of most individuals. Many depressed patients may benefit from higher doses, such as 20,000 IU / day (500 mcg), but such treatments allow you to test your level of vitamin D[ 25(OH)D] at least twice a year.
What does depression feel like?
Depression symptoms can slowly grow and may go unnoticed for a while. When this occurs, a friend or family member is often the first to note that your attitude or personality has changed. Depression symptoms may be physical, such as tiredness and muscle aches, and you may feel like you’re just under the weather or flu.
Below are some of the significant depression signs; however, symptoms vary from person to person.
- Loss of interest in life and lack of pleasure
- Deciding problems and focusing
- Most of the time, I feel unhappy
- Feeling tired and having trouble sleeping
- Loss of trust and self-esteem
- Antisocial behavior
- Feeling torpid, helpless and blank
- Change in appetite
When you feel these signs, and they do been going on for more than a couple of weeks, talk to your doctor.
What causes depression?
It seems that many factors can cause depression, but the exact cause is unknown. There is sometimes a significant trigger, like a loved one’s death, but there are several different factors that can play a part. While individuals vary in the factors leading to depression, the most common causes include:
- Significant changes in life–like divorce, change of job, move home or a loved one’s death
- Physical disease–particularly life-threatening illness such as cancer, painful conditions such as arthritis and hormonal problems such as an inactive thyroid gland
- Personal circumstances–for example, being alone or depressed
- Depression in family history
- Individual characteristics, particularly emotional resistivity
- Heavy drinking regularly
How common is depression?
Depression is a common disorder. Approximately 1 in 10 people in the United States have depression, and about 1 in 3 of these cases will be severe. Depression is more likely if you:
- Have a long-term health problem like diabetes, cardiac disease or arthritis
- Lead an unhealthy lifestyle, such as smoking, drinking heavily, being inactive or overweight
- They are women
- Between the ages of 45-64
- Hispanic or Black
What is the relation between depression and vitamin D?
In many aspects of human health, vitamin D plays a vital role, and scientists are now finding that vitamin D can also play a role in many other health fields.
Several parts of the brain have developed vitamin D receptors. Receptors are located on a cell’s surface and on the genes within the cell where chemical signals are received. Such chemical signals, and by the merge and with the receptor, direct a cell to do something, such as behaving in a certain way, dividing or dying.
Some of the brain receptors are vitamin D receptors, which means that vitamin D works in the brain somehow. These receptors are in the depression-related areas of the brain. But for this reason, vitamin D associated with depression and other mental health issues.
Whether vitamin D functions in the brain is not fully understood, one hypothesis is that vitamin D influences the number of chemicals called monoamines, such as serotonin, and how they work in mind.5 Most antidepressant drugs operate by increasing the number of monoamines in mind; indeed, but the enzyme which produces serotonin partially controlled by vitamin D. And studies have therefore proposed that vitamin D may also increase the number of monoamines that can be used to treat depression.
In general, what does the study say about vitamin D and depression?
The amount of vitamin D and anxiety research, as well as other mental health issues, is increasing. Just recently, large-scale work on vitamin D and anxiety has been carried out. But there have been some conflicting results from the study in this area.
Some of the reasons why vitamin D and depression research have reported mixed results include:
- Different dosages of vitamin D supplements are for different periods
- Different criteria for the adequacy and effectiveness of vitamin D treatment
- Populations in various studies
- Use of multiple tools for assessing depression and mental health
- Administering vitamin D at different frequencies–people are asked to take vitamin D daily in some studies, while people take vitamin once a week or once a month in other studies.
The amount of vitamin D given in some research studies was small but much less than five thousand IU to ten thousand IU a day recommended by the Vitamin D Council. Inadequate doses of vitamin D. Decrease the risk of generating significant medical results; the maxim in the medical field is that “the dose makes the medicine.”
Studies from the last few years have explicitly focused on levels of vitamin D and depression. For example, researchers analyzed all published research on depression and vitamin D in a summary of the literature on vitamin D and depression. These included the research studies of high quality which investigate:
- Vitamin D deficiencies in the blood increase the risk of somebody having depression
- Taking a supplement of vitamin D can boost or avoid depression
More than 5,000 examination articles found by the specialists; at the same time, exclusively thirteen were adequately investigating this space. In these thirteen reviews, more than 31,000 people took an interest. The outcomes demonstrated a connection between’s low blood cholecalciferol levels and sadness. The investigation has not appeared, in any case, regardless of whether cholecalciferol is that the reason or aftereffect of sorrow. There was conjointly no clear answer on whether it had been flourishing to fix or stay away from grief by taking enhancements.
A Norwegian research
The study showed more symptoms of depression in people with low levels of vitamin D in their blood. This study also found that taking vitamin D improved the symptoms of depression, especially in large quantities. The most significant effect for those with the most severe symptoms occurred.
However, this study just looked at people who were overweight, so it’s not possible to say if the findings for everyone would be identical. Additionally, both participants took a calcium supplement, and the researchers suggest that this might have affected the results; for example, the findings could be due to the combination of vitamin D and calcium rather than vitamin D alone.
And second Norwegian research study also examined whether the symptoms of depression related to blood levels of vitamin D. But she studies also investigated whether the symptoms of depression in people with low vitamin D levels are affected by taking a vitamin D supplement. And the results showed the following:
- Depression symptoms are associated with low levels of vitamin D in the body
- When people with low levels of vitamin D took a supplement, it improved their levels of vitamin D but did not affect their depression symptoms.
- The result could be low levels of vitamin D, rather than the cause of depression
Although this study used an appropriate dose of vitamin D supplement, it lasted just six months. Since depression is a disorder that appears to develop slowly and last for a long time, and the authors proposed that a more extensive study could have shown different results. Participants in the study also had either no depression symptoms or very mild symptoms that would, of course, affect the outcomes.
A study of people with ischemic stroke caused by blood clots in China found the prevalence of depression was much higher in people with low levels of vitamin D six months after the stroke than those with higher levels. Studies like this one are a reason to take enough doses of vitamin D if you have depression.
A Swedish study
Found that those who attempted suicide had significantly lower levels of vitamin D than patients who were depressed by non-suicide and controlled by nutrition. And we also had higher levels of pro-inflammatory cytokines found in other patients with suicide. Cytokines are small cell-emitted proteins that signal other cells. It is understood that vitamin D decreases pro-inflammatory cytokine levels.
A research in the Netherlands involving 1,102 people aged 18-65 with current depressive disorder and 790 with previous but not present depressive disorder found lower levels of vitamin D. Among those with current depressive disorder and more moderate severity of symptoms among those with higher levels of vitamin D. Vitamin D status also substantially associated with the occurrence of depressive symptoms at a 2-year follow-up. A cross-sectional analysis in Finland found a significant inverse correlation between vitamin D and depressive disorder. Those with levels of vitamin D above 22 ng / mL (56 nmol / L) had a 35% lower risk of the depressive disorder compared to those with levels of vitamin D below 14 ng / mL (34 nmol / L).